{"id":138808,"date":"2018-11-22T11:44:34","date_gmt":"2018-11-22T13:44:34","guid":{"rendered":"https:\/\/lab.fabricadelandings.com.br\/portalsaofrancisconovo\/?p=138808"},"modified":"2018-11-29T10:48:25","modified_gmt":"2018-11-29T12:48:25","slug":"neuroblastoma","status":"publish","type":"post","link":"https:\/\/lab.fabricadelandings.com.br\/portalsaofrancisconovo\/saude-e-bem-estar\/saude\/neuroblastoma","title":{"rendered":"Neuroblastoma"},"content":{"rendered":"<p><strong>O que \u00e9 neuroblastoma?<br \/>\n<\/strong><br \/>\nO neuroblastoma \u00e9 um tumor cancer\u00edgeno que come\u00e7a no tecido nervoso de lactentes e crian\u00e7as muito pequenas. As c\u00e9lulas anormais s\u00e3o frequentemente encontradas no tecido nervoso que est\u00e1 presente no feto e depois se desenvolve em um tumor detect\u00e1vel. O neuroblastoma \u00e9 raro em crian\u00e7as com mais de 10 anos de idade, no entanto, ocorre ocasionalmente em adultos.<\/p>\n<p>O tumor geralmente come\u00e7a nos tecidos da gl\u00e2ndula adrenal encontrada no abd\u00f4men, mas tamb\u00e9m pode come\u00e7ar no tecido nervoso do pesco\u00e7o, t\u00f3rax ou medula espinhal. As gl\u00e2ndulas supra-renais est\u00e3o posicionadas no topo dos rins. Essas gl\u00e2ndulas secretam horm\u00f4nios e outras subst\u00e2ncias importantes que s\u00e3o necess\u00e1rias para fun\u00e7\u00f5es normais no corpo.<\/p>\n<p>Frequentemente est\u00e1 presente ao nascimento, mas n\u00e3o detectado at\u00e9 que o tumor comece a crescer e comprimir os \u00f3rg\u00e3os circundantes. A maioria das crian\u00e7as afetadas pelo neuroblastoma foi diagnosticada antes dos 5 anos de idade. Em casos raros, o neuroblastoma pode ser detectado antes do nascimento por uma ultrassonografia fetal. \u00c9 o c\u00e2ncer de tumor s\u00f3lido mais comum em beb\u00eas.<\/p>\n<p>As c\u00e9lulas cancerosas do neuroblastoma podem se disseminar (metastatizar) rapidamente para outras \u00e1reas do corpo (por exemplo, linfonodos, f\u00edgado, pulm\u00f5es, ossos, sistema nervoso central e medula \u00f3ssea). Aproximadamente dois ter\u00e7os de todas as crian\u00e7as diagnosticadas com neuroblastoma ter\u00e3o alguma doen\u00e7a metast\u00e1tica.<\/p>\n<p><strong>O que \u00e9<\/strong><\/p>\n<p>O neuroblastoma em crian\u00e7as \u00e9 causado por neuroblastos que n\u00e3o amadurecem. Eles n\u00e3o se tornam os nervos normais ou c\u00e9lulas adrenais que devem amadurecer no nascimento. Esses neuroblastos imaturos formam um tumor.<\/p>\n<p>Durante o desenvolvimento no \u00fatero, um feto produz c\u00e9lulas nervosas imaturas. Ao nascer, esses neuroblastos devem se transformar em nervos e c\u00e9lulas adrenais que produzem fibras nervosas e gl\u00e2ndulas supra-renais. Na maioria dos rec\u00e9m-nascidos, uma pequena quantidade de neuroblastos imaturos n\u00e3o amadurece e geralmente desaparece. Para algumas crian\u00e7as, esses neuroblastos permanecem e formam um tumor cancer\u00edgeno.<\/p>\n<p>O neuroblastoma em crian\u00e7as geralmente est\u00e1 presente no nascimento. No entanto, muitas vezes n\u00e3o \u00e9 detectado at\u00e9 que um tumor apare\u00e7a e cause sintomas. A maioria das crian\u00e7as afetadas \u00e9 diagnosticada at\u00e9 os 5 anos de idade. Em casos raros, um tumor maligno \u00e9 detectado antes do nascimento em um ultrassom , mas n\u00e3o \u00e9 comum encontrar tumores antes dos 1 anos de idade.<\/p>\n<p>Os m\u00e9dicos acreditam que o neuroblastoma em crian\u00e7as \u00e9 causado por uma anomalia gen\u00e9tica no primeiro cromossomo. A extremidade curta desse cromossomo tem uma se\u00e7\u00e3o ausente ou rearranjada. Isso causa a amplifica\u00e7\u00e3o extra do oncogene conhecido como MYCN. Um oncogene \u00e9 um gene que causa c\u00e2ncer ao tornar uma c\u00e9lula maligna. Uma amplifica\u00e7\u00e3o de MYCN leva a um crescimento desregulado e r\u00e1pido de c\u00e9lulas cancer\u00edgenas .<\/p>\n<p>Fonte:\u00a0www.stanfordchildrens.org\/www.wisegeek.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>O que \u00e9 neuroblastoma? O neuroblastoma \u00e9 um tumor cancer\u00edgeno que come\u00e7a no tecido nervoso de lactentes e crian\u00e7as muito pequenas. As c\u00e9lulas anormais s\u00e3o frequentemente encontradas no tecido nervoso que est\u00e1 presente no feto e depois se desenvolve em um tumor detect\u00e1vel. O neuroblastoma \u00e9 raro em crian\u00e7as com mais de 10 anos de [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":139204,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[84],"tags":[],"class_list":["post-138808","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saude"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Neuroblastoma, O que \u00e9 Neuroblastoma<\/title>\n<meta name=\"description\" content=\"Neuroblastoma, O que \u00e9, Sintomas, Crian\u00e7as, Cromossomo, Doen\u00e7a, Exames Neuroblastoma\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" 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